The best Side of akorn codeine
The best Side of akorn codeine
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Lifetime-Threatening Respiratory Depression Advise clients of the potential risk of existence-threatening respiratory despair, which includes information and facts that the risk is biggest when beginning promethazine HCl and codeine phosphate oral Resolution and that it could possibly occur even at proposed dosages [see Warnings and Safety measures (five.
Promethazine Hydrochloride and Codeine Phosphate Oral Resolution is really a prescription medication Utilized in adults to temporarily deal with cough and upper respiratory signs and symptoms you can have with allergy symptoms or a typical cold.
are pregnant. Use of Promethazine Hydrochloride and Codeine Phosphate Oral Alternative in the course of pregnancy could potentially cause withdrawal indications in your new child newborn that may be existence-threatening Otherwise acknowledged and addressed. Inform your healthcare supplier instantly In case you are pregnant or Consider you might be pregnant. •
The phosphate salt of codeine occurs as white, needle-shaped crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and marginally soluble in alcohol. The molecular excess weight is 406.37. Its molecular formula is C18H21NO3•H3PO4 • ½ H2O, and it has the following chemical composition.
Existence-threatening breathing issues (respiratory depression). Promethazine Hydrochloride and Codeine Phosphate Oral Alternative may cause respiration challenges (respiratory melancholy) which can transpire at any time throughout treatment and can lead to Demise. Your threat of respiratory complications is best after you 1st commence getting Promethazine Hydrochloride and Codeine Phosphate Oral Option, are taking other medicines that could potentially cause respiratory problems, have selected lung issues, are elderly or have sure other medical problems.
Promethazine HCl and codeine phosphate oral Alternative must be made use of with warning in patients with impairment of hepatic purpose, and people should be monitored carefully for respiratory melancholy, sedation, and hypotension.
INDICATIONS AND USAGE Promethazine HCl and codeine phosphate oral Alternative is a combination of codeine, an opioid agonist, and promethazine, a phenothiazine, indicated to the short-term relief of cough and upper respiratory signs and symptoms related to allergy or perhaps the common chilly in sufferers eighteen several years of age and older. (1) (1)
When you've got any prescription drugs which were created by Akorn, industry experts endorse reaching out on your pharmacist or healthcare company to debate option medication alternatives.
Avoid the usage of promethazine HCl and codeine phosphate oral Remedy in patients using muscle mass relaxants. If concomitant use read more is important, watch sufferers for indications of respiratory melancholy that may be larger than otherwise predicted.
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Lactation At the least one death was noted inside of a nursing infant who was subjected to superior levels of morphine in breast milk since the mom was an extremely-fast metabolizer of codeine.
Promethazine Promethazine competitively antagonize H1 receptors located in the majority of the easy muscle mass including the gastrointestinal tract, uterus, huge blood vessels and bronchial muscle mass.
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If adrenal insufficiency is diagnosed, take care of with physiologic alternative doses of corticosteroids. Wean the affected person off with the opioid to permit adrenal purpose to Get well and continue on corticosteroid procedure until finally adrenal perform recovers. Other opioids could possibly be tried as some situations documented utilization of a special opioid devoid of recurrence of adrenal insufficiency. The knowledge obtainable will not discover any certain opioids as getting much more very likely to be affiliated with adrenal insufficiency.